Nolvadex is the trade name for drug tamoxifen citrate which is an antagonist for estrogen that is used as a first line of clinical defense against carcinomas of breast. Nolvadex is somewhat different from other products since it is not an anabolic/androgenic steroid.
Mode of Action:
The drug is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors in various target tissues. It is, however, important to understand that Nolvadex does not prevent testosterone and its synthetic derivatives, so called anabolic steroids, from converting into estrogens but only fights with them in a sort of “competition” for the estrogen receptors and prevents the downstream signaling pathways initiated by estrogen.
Therapeutic uses of Nolvadex:
Being an estrogen antagonist, Nolvadex has a range of documented therapeutic uses:
0 Gynecomastia prevention: Nolvadex prevents gynecomastia (excessive development of the breasts in males) by competitively binding to the estrogen receptors the breast tissue and preventing estrogen associated breast development.
0 Breast Carcinoma: Nolvadex has been utilized successfully as a preventive medicine by people with an extremely high susceptibility for breast cancer, for instance, people with family history of breast cancers. However, it is important to realize that breast cancers may or may not be estrogen associated and as they are […]
Full Article At: KnowHow-Now.com Articles
Confusion continues to overshadow our choice of proper nutritional supplements. We have such a wide variety of vitamins and food supplements, however, people are just as confused as they were 10 years ago.How can we figure out what is best for us? Up until a few years ago, I was content with taking a One-a -Day multi-vitamin. Sometimes, I didn’t have energy, but I attributed it to lack of sleep or not eating properly. Occasionally, my immune system was not up to par and I was coming down with colds and infections.After many years of working in the stressful legal and corporate environment, I decided to work from home. I sold natural vitamins and food supplements. All of the products were deemed to be without synthetics, chemicals or fillers. In order for me to sell them, I had to familiarize myself with all of the products, ailments, diseases, and afflictions. This equipped me with the sales acumen to “up-sell” additional products.To insure that I myself would never have to suffer from heart disease, joint pain, diabetes, intestinal worms, cancer, high blood pressure, hot flashes, depression, bone loss, or whatever else that may be lurking around the corner, I took most […]
Full Article At: KnowHow-Now.com Articles
The hot flash is the scourge of the middle-aged woman - you’ve no doubt heard the battle cry, “Is it hot in here, or is it just me?” The prickling of the skin, rapid heart beat, pressure in your head… your skin flushes, you feel anxious, maybe a little dizzy, the sweat starts pouring off of you. All of it unpleasant, but the worst part is, you never know when it’s going to come, how long it’s going to last, or how bad it will be. In an ideal world, hot flashes would only occur when you’re alone and naked in a cold shower.Hot flashes are often the precursor which alerts you to a major bodily upheaval - the menopause, or the cessation of the menstrual cycle. It’s an oxymoron to use the article “the” to identify it –”the menopause,” as though it’s a single fixed moment in time. Shoot, for some women, the period between the first hot flash and the actual end of your menstrual periods can be years.So, with the “good news” that your hot flashes may last for months on end until you actually are officially “menopausal,” what can you do […]
Full Article At: KnowHow-Now.com Articles
