Health care practitioners documented benefits in premenopausal and menopausal symptoms including reduction in hot flashes and improvement of “depressive moods.” Furthering the advancements, five clinical studies since 1979 have compared Black Cohosh extra
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How to recognise the onset of Menopause
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Nolvadex is the trade name for drug tamoxifen citrate which is an antagonist for estrogen that is used as a first line of clinical defense against carcinomas of breast. Nolvadex is somewhat different from other products since it is not an anabolic/androgenic steroid.
Mode of Action:
The drug is technically an estrogen agonist/antagonist, which competitively binds to estrogen receptors in various target tissues. It is, however, important to understand that Nolvadex does not prevent testosterone and its synthetic derivatives, so called anabolic steroids, from converting into estrogens but only fights with them in a sort of “competition” for the estrogen receptors and prevents the downstream signaling pathways initiated by estrogen.
Therapeutic uses of Nolvadex:
Being an estrogen antagonist, Nolvadex has a range of documented therapeutic uses:
0 Gynecomastia prevention: Nolvadex prevents gynecomastia (excessive development of the breasts in males) by competitively binding to the estrogen receptors the breast tissue and preventing estrogen associated breast development.
0 Breast Carcinoma: Nolvadex has been utilized successfully as a preventive medicine by people with an extremely high susceptibility for breast cancer, for instance, people with family history of breast cancers. However, it is important to realize that breast cancers may or may not be estrogen associated and as they are […]
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Tags: estrogen receptors, target tissues, breast carcinoma, breast cancers, drug tamoxifen